Frazier joined Oregon State’s Horticulture Department in 1949, coming from the University of Hawaii. At Oregon State, he worked on breeding new varieties of vegetables with his student and fellow faculty member Jim Baggett. They are known for the developing a bush variety of the Blue Lake green bean, which enabled farmers to mechanically harvest this popular variety. Frazier also developed the Willamette tomato, one of the first varieties developed for the Willamette Valley and still popular with home gardeners.
The SMILE program (Science and Math Investigative Learning Experiences) was created at OSU in 1988. SMILE seeks to promote interest in the STEM fields among Oregon's minority and under-served youth, and to encourage these students to attend college, by involving them in science- and math-based extracurricular activities.
The lab was established in 1981 in the School of Health and Physical Education. Today the lab, one of nine research labs in the College of Public Health and Human Sciences, is used for studies pertaining to exercise energy metabolism, athletic performance, and body composition.