Frazier joined Oregon State’s Horticulture Department in 1949, coming from the University of Hawaii. At Oregon State, he worked on breeding new varieties of vegetables with his student and fellow faculty member Jim Baggett. They are known for the developing a bush variety of the Blue Lake green bean, which enabled farmers to mechanically harvest this popular variety. Frazier also developed the Willamette tomato, one of the first varieties developed for the Willamette Valley and still popular with home gardeners.
The Horticulture class was on a class trip to the Southern Oregon Experiment Station. Frank Charles Reimer was the Superintendent of the Southern Oregon Experiment Station. One of his focuses was locating pear trees that were resistant to Fireblight.